December 12th, 2017
Current methods of estimating absorbed dosage (AD) of chemicals were evaluated to determine residue transfer from a carpet treated with chlorpyrifos (CP) to humans who performed a structured exercise routine. To determine the dislodgeability of residue, a California Department of Food andAgriculture (CDFA) roller was applied to a flat cotton cloth upon a treated carpet. Levels ranged from 0.06 to 0.99 µg CP/cm2. Cotton whole body disimeters (WBD) were also used to assess residue transer. The dosimeters retained 1.5 to 38 mg CP/person. Urine biomonitoring (3 days) for 3, 5, 6-trichloro-2-pyridinol (TCP) of persons who wore only swimsuits revealed a meanAD of 176 µg CP equivalents/person. The results show that theAD depends on the extend of contact transfer and dermal absorption of the residue. Default exposure assessments based upon environmental levels of chemicals and hypothetical transport pathways predict excessive exposure. The cotton WBD retains chemical residues and may be effectively used to preduct dermal dose under experimental conditions. Journal of ExposureAnalysis and Environmental Epidemiology (2000) 10, 50-57